پایان نامه سنتز نانو ذرات مغناطیسی با پوشش طلا مزدوج شده با سیستامین به عنوان عامل انتقال دارو

فهرست و منابع پایان نامه سنتز نانو ذرات مغناطیسی با پوشش طلا مزدوج شده با سیستامین به عنوان عامل انتقال دارو

فهرست:

فصل اول....................................................................................................................................................1

1-1 مقدمه.................................................................................................................................................2

1-2 نانو فناوری.........................................................................................................................................8

1-3 نانو ذرات.........................................................................................................................................10

1-4 طبقه بندی نانو ذرات.......................................................................................................................11

1-4-1 سوپر پارامغناطیس.......................................................................................................................11

1-4-2 نانو ذرات فلزی..........................................................................................................................12

1-4-3 نانو مواد سه بعدی.......................................................................................................................15

1-4-4 نانو مواد دو بعدی.......................................................................................................................15

1-4-5 نانو مواد تک بعدی......................................................................................................................16

1-4-6 نانو لوله ها...................................................................................................................................16

1-4-7 نانو میله های طلا .......................................................................................................................16

1-4-8 نانو سیم ها..................................................................................................................................18

1-4-9 نانو مواد صفر بعدی....................................................................................................................18

1-4-10 نقاط کوانتومی..........................................................................................................................18

1-4-11 نانو ذرات لپیدی......................................................................................................................19

1-4-12 نانو ذرات پلیمری....................................................................................................................20

1-5 نانو ذرات طلا................................................................................................................................21

1-6 خواص نوری نانو ذرات طلا..........................................................................................................23

1-7 انواع پلاسمون سطحی....................................................................................................................24

1-8 محاسبات کمی خواص نوری نانو ذرات طلا..................................................................................28

1-9 پارامترهای موثر در طراحی نانو ذرات مغناطیسی............................................................................32

1-9-1 موانع فیزیولوژیکی......................................................................................................................32

1-9-2 پارامترهای فیزیکی......................................................................................................................34

1-9-3  اندازه هیدرودینامیک..................................................................................................................34

1-10 مزایایی پوشش دار کردن سطح نانو ذرات.....................................................................................36

1-11 موانع در کاربردهای پزشکی..........................................................................................................37

1-12 نتیجه گیری....................................................................................................................................38

فصل دوم.........................................................................................................................40

2-1 سیستامین..........................................................................................................................................41

2-2 فاموتیدین.........................................................................................................................................42

2-3 مروری بر کارهای انجام گرفته.........................................................................................................42

2-3-1 توموگرافی محاسبه شده اشعه ایکس...........................................................................................48

2-3-2 حسی زیستی...............................................................................................................................50

2-4 مطالعه سمیت نانو ذرات مغناطیسی.................................................................................................52

فصل سوم................................................................................................................................................55

3-1 واکنشگر ها......................................................................................................................................56

3-2 تهییه محول ها..................................................................................................................................57

3-3 دستگاه ها.........................................................................................................................................57

3-4 روش تولید نانو ذره آهن.................................................................................................................58

3-5 روش پوشش دهی نانو ذره آهن با طلا............................................................................................60

3-6 در مجاورت قرار دادن سیستامین و نانو ذره....................................................................................61

3-7 روش محاسبه غلظت تقریبی نانو ذرات طلا....................................................................................61

فصل چهارم.............................................................................................................................................62

4-1 مقدمه..............................................................................................................................................63

4-2 طیف FT-IR از نانو ذره آهن.........................................................................................................64

4-3 تائید پوشش دهی نانو ذره آهن با طلا.............................................................................................65

4-4 قرار دادن نانو ذره آهن پوشش داده شده با طلا در مجاورت سیستامین..........................................66

4-5 تعیین زمان بهینه جذب....................................................................................................................66

4-5-1 تعیین زمان بهینه جذب 0.1 مولار سیستامین..............................................................................66

4-5-2 تعیین زمان بهینه جذب 0.5 مولار سیستامین.............................................................................67

4-5-3 تعیین زمان بهینه جذب 0.05 مولار سیستامین............................................................................68

4-6 تعیین غلظت بهینه جذب ...............................................................................................................69

4-7 تعیین  pH بهینه جذب...................................................................................................................70

4-8 بررسی نتایج زمان بهینه جذب.........................................................................................................71

4-9 بررسی نتایج غلظت بهینه جذب......................................................................................................75

4-10 بررسی نتایج pH بهینه جذب........................................................................................................

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